Health
Ultra-Processed Foods Harm Men’s Metabolism and Fertility, Study Finds

A recent study conducted by researchers at the University of Copenhagen reveals that ultra-processed foods (UPFs) can significantly impact men’s metabolism and fertility. This effect persists even when calorie and macronutrient intake is controlled. The research highlights the urgent need to reconsider dietary guidelines, particularly regarding the consumption of highly processed foods.
The study involved 43 men aged between 20 and 35 who followed two distinct diets for three weeks each: one composed of ultra-processed foods and another featuring minimally processed options. The ultra-processed diet included items such as ready-to-eat meals, sweetened cereals, processed meats, packaged breads, flavored yogurts, and soft drinks. In contrast, the whole-foods diet consisted of fresh fruits and vegetables, eggs, meat, fish, whole grains, legumes, plain dairy products, and nuts and seeds.
Findings from the study indicate significant differences in health outcomes between the two diets. Participants on the ultra-processed diet gained approximately 2 pounds of fat mass and exhibited worse heart health markers compared to those on the minimally processed diet. The researchers noted that the body metabolizes calories from ultra-processed foods differently, even when the macronutrient composition is similar.
Health Implications of Ultra-Processed Diets
Further analysis revealed that men consuming ultra-processed foods had elevated levels of environmental pollutants associated with reduced sperm quality, including a phthalate chemical known as cxMINP. Additionally, participants demonstrated decreased levels of testosterone and follicle-stimulating hormone (FSH), both of which are critical for sperm production. The study underscores that the risks associated with ultra-processed food consumption extend beyond simple calorie counts.
According to Romain Barrès, the senior author of the study, the results were startling. He expressed concern over the numerous bodily functions disrupted by ultra-processed foods, even in otherwise healthy young men. The findings suggest that a shift toward less-processed dietary options could also provide mental health benefits.
Despite the compelling results, the researchers acknowledged limitations in their study, including the relatively small sample size and the short duration of the dietary interventions. Such factors may introduce bias and limit the generalizability of the findings.
Experts in the field, including Dr. David Shusterman, emphasize that this research adds a crucial piece to understanding the relationship between diet quality and men’s health. The study highlights potential endocrine and fertility risks associated with food processing itself. Furthermore, Dr. Justin Houman cautioned against applying these findings to older men or those with pre-existing health conditions without further research. He also pointed out that, in practical terms, the effects of ultra-processed foods might be even more pronounced due to their tendency to contribute to overall increased calorie intake.
Need for Revised Nutritional Guidelines
The prevalence of ultra-processed foods is a growing concern, particularly in diets like that of the average American, where UPFs now constitute more than half of total food consumption. This study’s results signal an urgent need to reassess nutritional guidelines to better protect against chronic diseases linked to poor dietary choices.
Overall, the research reinforces the critical importance of opting for less-processed foods to maintain optimal health. As the debate over dietary practices continues, this study serves as a reminder that the quality of food consumed can have profound impacts on both metabolic and reproductive health.
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